Gene description for TSG101
Gene name	tumor susceptibility 101
Gene symbol	TSG101
Other names/aliases	-
Species	Bos taurus
Experiment description of studies that identified TSG101 in Bovine milk
1 Experiment ID 439 Identified molecule protein Extracellular vesicle type Exosomes/Membrane vesicles MISEV EVs Identification method Mass spectrometry PubMed ID 22129587    Organism Bos taurus Experiment description Bovine milk exosome proteome. Authors Reinhardt TA, Lippolis JD, Nonnecke BJ, Sacco RE. Journal name J Proteomics Publication year 2012 Sample Bovine milk Sample name Normal cow-Milk Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV120041: EV-METRIC:56%
2 Experiment ID 503 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 23459212    Organism Bos taurus Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis. Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD. Journal name J Proteomics Publication year 2013 Sample Bovine milk Sample name Staphylococcus aureus-infected-Milk Isolation/purification methods - Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130111: EV-METRIC:43%
3 Experiment ID 1045 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry Western blotting PubMed ID 28725021    Organism Bos taurus Experiment description Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth. Authors Samuel M, Chisanga D, Liem M, Keerthikumar S, Anand S, Ang CS, Adda CG, Versteegen E, Jois M, Mathivanan S. Journal name Sci Rep. Publication year 2017 Sample Bovine milk Sample name Bovine milk - colostrum 12 h and 24 h Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density 1.08.1.24 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK -
4 Experiment ID 1046 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry Western blotting PubMed ID 28725021    Organism Bos taurus Experiment description Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth. Authors Samuel M, Chisanga D, Liem M, Keerthikumar S, Anand S, Ang CS, Adda CG, Versteegen E, Jois M, Mathivanan S. Journal name Sci Rep. Publication year 2017 Sample Bovine milk Sample name Bovine milk - colostrum 72 h Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density 1.08.1.24 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK -
5 Experiment ID 1047 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry Western blotting PubMed ID 28725021    Organism Bos taurus Experiment description Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth. Authors Samuel M, Chisanga D, Liem M, Keerthikumar S, Anand S, Ang CS, Adda CG, Versteegen E, Jois M, Mathivanan S. Journal name Sci Rep. Publication year 2017 Sample Bovine milk Sample name Bovine milk - colostrum 48 h Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density 1.08.1.24 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK -
6 Experiment ID 1048 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry Western blotting PubMed ID 28725021    Organism Bos taurus Experiment description Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth. Authors Samuel M, Chisanga D, Liem M, Keerthikumar S, Anand S, Ang CS, Adda CG, Versteegen E, Jois M, Mathivanan S. Journal name Sci Rep. Publication year 2017 Sample Bovine milk Sample name Bovine milk - mature milk Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density 1.08.1.24 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting EV-TRACK -
7 Experiment ID 1163 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Western blotting PubMed ID 29904572    Organism Bos taurus Experiment description A subset of extracellular vesicles carries the bulk of microRNAs in commercial dairy cow's milk. Authors Benmoussa A, Ly S, Shan ST, Laugier J, Boilard E, Gilbert C, Provost P. Journal name J Extracell Vesicles Publication year 2017 Sample Bovine milk Sample name Pellet, 12000 g Isolation/purification methods Differential centrifugation Density gradient centrifugation Flotation density 1.11-1.14 g/mL Molecules identified in the study Protein miRNA Methods used in the study Mass spectrometry Western blotting EV-TRACK -
8 Experiment ID 1164 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Western blotting PubMed ID 29904572    Organism Bos taurus Experiment description A subset of extracellular vesicles carries the bulk of microRNAs in commercial dairy cow's milk. Authors Benmoussa A, Ly S, Shan ST, Laugier J, Boilard E, Gilbert C, Provost P. Journal name J Extracell Vesicles Publication year 2017 Sample Bovine milk Sample name Pellet, 35000 g Isolation/purification methods Differential centrifugation Density gradient centrifugation Flotation density 1.11-1.14 g/mL Molecules identified in the study Protein miRNA Methods used in the study Mass spectrometry Western blotting EV-TRACK -
9 Experiment ID 1165 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Western blotting PubMed ID 29904572    Organism Bos taurus Experiment description A subset of extracellular vesicles carries the bulk of microRNAs in commercial dairy cow's milk. Authors Benmoussa A, Ly S, Shan ST, Laugier J, Boilard E, Gilbert C, Provost P. Journal name J Extracell Vesicles Publication year 2017 Sample Bovine milk Sample name Pellet, 70000 g Isolation/purification methods Differential centrifugation Density gradient centrifugation Flotation density 1.11-1.14 g/mL Molecules identified in the study Protein miRNA Methods used in the study Mass spectrometry Western blotting EV-TRACK -
10 Experiment ID 1166 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV EVs Identification method Western blotting PubMed ID 29904572    Organism Bos taurus Experiment description A subset of extracellular vesicles carries the bulk of microRNAs in commercial dairy cow's milk. Authors Benmoussa A, Ly S, Shan ST, Laugier J, Boilard E, Gilbert C, Provost P. Journal name J Extracell Vesicles Publication year 2017 Sample Bovine milk Sample name Pellet, 100000 g Isolation/purification methods Differential centrifugation Density gradient centrifugation Flotation density 1.11-1.14 g/mL Molecules identified in the study Protein miRNA Methods used in the study Mass spectrometry Western blotting EV-TRACK -
11 Experiment ID 2193 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 29511463    Organism Bos taurus Experiment description Biocompatibility of highly purified bovine milk-derived extracellular vesicles Authors Somiya M, Yoshioka Y, Ochiya T. Journal name J Extracell Vesicles Publication year 2018 Sample Bovine milk Sample name Commercial milk - deffated Isolation/purification methods Acidification Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
12 Experiment ID 2194 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 29511463    Organism Bos taurus Experiment description Biocompatibility of highly purified bovine milk-derived extracellular vesicles Authors Somiya M, Yoshioka Y, Ochiya T. Journal name J Extracell Vesicles Publication year 2018 Sample Bovine milk Sample name Commercial milk - deffated Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
13 Experiment ID 2211 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 37043568    Organism Bos taurus Experiment description Milk-derived extracellular vesicles protect intestinal barrier integrity in the gut-liver axis Authors Tong L, Zhang S, Liu Q, Huang C, Hao H, Tan MS, Yu X, Lou CKL, Huang R, Zhang Z, Liu T, Gong P, Ng CH, Muthiah M, Pastorin G, Wacker MG, Chen X, Storm G, Lee CN, Zhang L, Yi H, Wang JW. Journal name Sci Adv Publication year 2023 Sample Bovine milk Sample name Colostrum Isolation/purification methods Differential centrifugation Ultracentrifugation Centrifugal ultrafiltration Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
14 Experiment ID 2258 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 37376799    Organism Bos taurus Experiment description Bovine milk-derived extracellular vesicles enhance doxorubicin sensitivity in triple negative breast cancer cells by targeting metabolism and STAT signalling Authors Sanwlani R, Kang T, Gummadi S, Nedeva C, Ang CS, Mathivanan S. Journal name Proteomics Publication year 2023 Sample Bovine milk Sample name Commercial milk Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
15 Experiment ID 2567 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 33805332    Organism Bos taurus Experiment description Temporal Quantitative Proteomics Analysis of Neuroblastoma Cells Treated with Bovine Milk-Derived Extracellular Vesicles Highlights the Anti-Proliferative Properties of Milk-Derived Extracellular Vesicles Authors Fonseka P, Kang T, Chee S, Chitti SV, Sanwlani R, Ang CS, Mathivanan S. Journal name Cells Publication year 2021 Sample Bovine milk Sample name Commercial milk Isolation/purification methods Differential centrifugation Ultracentrifugation Filtration Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
16 Experiment ID 2796 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 34168137    Organism Bos taurus Experiment description Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Authors Samuel M, Fonseka P, Sanwlani R, Gangoda L, Chee SH, Keerthikumar S, Spurling A, Chitti SV, Zanker D, Ang CS, Atukorala I, Kang T, Shahi S, Marzan AL, Nedeva C, Vennin C, Lucas MC, Cheng L, Herrmann D, Pathan M, Chisanga D, Warren SC, Zhao K, Abraham N, Anand S, Boukouris S, Adda CG, Jiang L, Shekhar TM, Baschuk N, Hawkins CJ, Johnston AJ, Orian JM, Hoogenraad NJ, Poon IK, Hill AF, Jois M, Timpson P, Parker BS, Mathivanan S. Journal name Nat Commun Publication year 2021 Sample Bovine milk Sample name Raw milk - Fraction 5 Isolation/purification methods Differential centrifugation OptiPrep density gradient centrifugation Ultracentrifugation Flotation density 1.08 g/mL Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
17 Experiment ID 2797 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 34168137    Organism Bos taurus Experiment description Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Authors Samuel M, Fonseka P, Sanwlani R, Gangoda L, Chee SH, Keerthikumar S, Spurling A, Chitti SV, Zanker D, Ang CS, Atukorala I, Kang T, Shahi S, Marzan AL, Nedeva C, Vennin C, Lucas MC, Cheng L, Herrmann D, Pathan M, Chisanga D, Warren SC, Zhao K, Abraham N, Anand S, Boukouris S, Adda CG, Jiang L, Shekhar TM, Baschuk N, Hawkins CJ, Johnston AJ, Orian JM, Hoogenraad NJ, Poon IK, Hill AF, Jois M, Timpson P, Parker BS, Mathivanan S. Journal name Nat Commun Publication year 2021 Sample Bovine milk Sample name Raw milk - Fraction 6 Isolation/purification methods Differential centrifugation OptiPrep density gradient centrifugation Ultracentrifugation Flotation density 1.10 g/mL Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
18 Experiment ID 2798 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small Evs Identification method Western blotting PubMed ID 34168137    Organism Bos taurus Experiment description Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Authors Samuel M, Fonseka P, Sanwlani R, Gangoda L, Chee SH, Keerthikumar S, Spurling A, Chitti SV, Zanker D, Ang CS, Atukorala I, Kang T, Shahi S, Marzan AL, Nedeva C, Vennin C, Lucas MC, Cheng L, Herrmann D, Pathan M, Chisanga D, Warren SC, Zhao K, Abraham N, Anand S, Boukouris S, Adda CG, Jiang L, Shekhar TM, Baschuk N, Hawkins CJ, Johnston AJ, Orian JM, Hoogenraad NJ, Poon IK, Hill AF, Jois M, Timpson P, Parker BS, Mathivanan S. Journal name Nat Commun Publication year 2021 Sample Bovine milk Sample name Raw milk - Fraction 7 Isolation/purification methods Differential centrifugation OptiPrep density gradient centrifugation Ultracentrifugation Flotation density 1.12 g/mL Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
19 Experiment ID 2799 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 34168137    Organism Bos taurus Experiment description Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Authors Samuel M, Fonseka P, Sanwlani R, Gangoda L, Chee SH, Keerthikumar S, Spurling A, Chitti SV, Zanker D, Ang CS, Atukorala I, Kang T, Shahi S, Marzan AL, Nedeva C, Vennin C, Lucas MC, Cheng L, Herrmann D, Pathan M, Chisanga D, Warren SC, Zhao K, Abraham N, Anand S, Boukouris S, Adda CG, Jiang L, Shekhar TM, Baschuk N, Hawkins CJ, Johnston AJ, Orian JM, Hoogenraad NJ, Poon IK, Hill AF, Jois M, Timpson P, Parker BS, Mathivanan S. Journal name Nat Commun Publication year 2021 Sample Bovine milk Sample name Raw milk - Fraction 8 Isolation/purification methods Differential centrifugation OptiPrep density gradient centrifugation Ultracentrifugation Flotation density 1.16 g/mL Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
20 Experiment ID 2800 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 34168137    Organism Bos taurus Experiment description Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Authors Samuel M, Fonseka P, Sanwlani R, Gangoda L, Chee SH, Keerthikumar S, Spurling A, Chitti SV, Zanker D, Ang CS, Atukorala I, Kang T, Shahi S, Marzan AL, Nedeva C, Vennin C, Lucas MC, Cheng L, Herrmann D, Pathan M, Chisanga D, Warren SC, Zhao K, Abraham N, Anand S, Boukouris S, Adda CG, Jiang L, Shekhar TM, Baschuk N, Hawkins CJ, Johnston AJ, Orian JM, Hoogenraad NJ, Poon IK, Hill AF, Jois M, Timpson P, Parker BS, Mathivanan S. Journal name Nat Commun Publication year 2021 Sample Bovine milk Sample name Raw milk - Fraction 9 Isolation/purification methods Differential centrifugation OptiPrep density gradient centrifugation Ultracentrifugation Flotation density 1.22 g/mL Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
21 Experiment ID 2801 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 34168137    Organism Bos taurus Experiment description Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Authors Samuel M, Fonseka P, Sanwlani R, Gangoda L, Chee SH, Keerthikumar S, Spurling A, Chitti SV, Zanker D, Ang CS, Atukorala I, Kang T, Shahi S, Marzan AL, Nedeva C, Vennin C, Lucas MC, Cheng L, Herrmann D, Pathan M, Chisanga D, Warren SC, Zhao K, Abraham N, Anand S, Boukouris S, Adda CG, Jiang L, Shekhar TM, Baschuk N, Hawkins CJ, Johnston AJ, Orian JM, Hoogenraad NJ, Poon IK, Hill AF, Jois M, Timpson P, Parker BS, Mathivanan S. Journal name Nat Commun Publication year 2021 Sample Bovine milk Sample name Commercial milk - Fraction 5 Isolation/purification methods Differential centrifugation OptiPrep density gradient centrifugation Ultracentrifugation Flotation density 1.08 g/mL Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
22 Experiment ID 2802 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 34168137    Organism Bos taurus Experiment description Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Authors Samuel M, Fonseka P, Sanwlani R, Gangoda L, Chee SH, Keerthikumar S, Spurling A, Chitti SV, Zanker D, Ang CS, Atukorala I, Kang T, Shahi S, Marzan AL, Nedeva C, Vennin C, Lucas MC, Cheng L, Herrmann D, Pathan M, Chisanga D, Warren SC, Zhao K, Abraham N, Anand S, Boukouris S, Adda CG, Jiang L, Shekhar TM, Baschuk N, Hawkins CJ, Johnston AJ, Orian JM, Hoogenraad NJ, Poon IK, Hill AF, Jois M, Timpson P, Parker BS, Mathivanan S. Journal name Nat Commun Publication year 2021 Sample Bovine milk Sample name Commercial milk - Fraction 6 Isolation/purification methods Differential centrifugation OptiPrep density gradient centrifugation Ultracentrifugation Flotation density 1.10 g/mL Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
23 Experiment ID 2803 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 34168137    Organism Bos taurus Experiment description Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Authors Samuel M, Fonseka P, Sanwlani R, Gangoda L, Chee SH, Keerthikumar S, Spurling A, Chitti SV, Zanker D, Ang CS, Atukorala I, Kang T, Shahi S, Marzan AL, Nedeva C, Vennin C, Lucas MC, Cheng L, Herrmann D, Pathan M, Chisanga D, Warren SC, Zhao K, Abraham N, Anand S, Boukouris S, Adda CG, Jiang L, Shekhar TM, Baschuk N, Hawkins CJ, Johnston AJ, Orian JM, Hoogenraad NJ, Poon IK, Hill AF, Jois M, Timpson P, Parker BS, Mathivanan S. Journal name Nat Commun Publication year 2021 Sample Bovine milk Sample name Commercial milk - Fraction 7 Isolation/purification methods Differential centrifugation OptiPrep density gradient centrifugation Ultracentrifugation Flotation density 1.12 g/mL Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
24 Experiment ID 2804 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 34168137    Organism Bos taurus Experiment description Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Authors Samuel M, Fonseka P, Sanwlani R, Gangoda L, Chee SH, Keerthikumar S, Spurling A, Chitti SV, Zanker D, Ang CS, Atukorala I, Kang T, Shahi S, Marzan AL, Nedeva C, Vennin C, Lucas MC, Cheng L, Herrmann D, Pathan M, Chisanga D, Warren SC, Zhao K, Abraham N, Anand S, Boukouris S, Adda CG, Jiang L, Shekhar TM, Baschuk N, Hawkins CJ, Johnston AJ, Orian JM, Hoogenraad NJ, Poon IK, Hill AF, Jois M, Timpson P, Parker BS, Mathivanan S. Journal name Nat Commun Publication year 2021 Sample Bovine milk Sample name Commercial milk - Fraction 8 Isolation/purification methods Differential centrifugation OptiPrep density gradient centrifugation Ultracentrifugation Flotation density 1.16 g/mL Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
25 Experiment ID 2805 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 34168137    Organism Bos taurus Experiment description Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Authors Samuel M, Fonseka P, Sanwlani R, Gangoda L, Chee SH, Keerthikumar S, Spurling A, Chitti SV, Zanker D, Ang CS, Atukorala I, Kang T, Shahi S, Marzan AL, Nedeva C, Vennin C, Lucas MC, Cheng L, Herrmann D, Pathan M, Chisanga D, Warren SC, Zhao K, Abraham N, Anand S, Boukouris S, Adda CG, Jiang L, Shekhar TM, Baschuk N, Hawkins CJ, Johnston AJ, Orian JM, Hoogenraad NJ, Poon IK, Hill AF, Jois M, Timpson P, Parker BS, Mathivanan S. Journal name Nat Commun Publication year 2021 Sample Bovine milk Sample name Commercial milk - Fraction 9 Isolation/purification methods Differential centrifugation OptiPrep density gradient centrifugation Ultracentrifugation Flotation density 1.22 g/mL Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
26 Experiment ID 2807 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 34168137    Organism Bos taurus Experiment description Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Authors Samuel M, Fonseka P, Sanwlani R, Gangoda L, Chee SH, Keerthikumar S, Spurling A, Chitti SV, Zanker D, Ang CS, Atukorala I, Kang T, Shahi S, Marzan AL, Nedeva C, Vennin C, Lucas MC, Cheng L, Herrmann D, Pathan M, Chisanga D, Warren SC, Zhao K, Abraham N, Anand S, Boukouris S, Adda CG, Jiang L, Shekhar TM, Baschuk N, Hawkins CJ, Johnston AJ, Orian JM, Hoogenraad NJ, Poon IK, Hill AF, Jois M, Timpson P, Parker BS, Mathivanan S. Journal name Nat Commun Publication year 2021 Sample Bovine milk Sample name Commercial milk - Fractions 6-8 pooled Isolation/purification methods Differential centrifugation OptiPrep density gradient centrifugation Ultracentrifugation Flotation density 1.10-1.16 g/mL Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
27 Experiment ID 2815 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 34168137    Organism Bos taurus Experiment description Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Authors Samuel M, Fonseka P, Sanwlani R, Gangoda L, Chee SH, Keerthikumar S, Spurling A, Chitti SV, Zanker D, Ang CS, Atukorala I, Kang T, Shahi S, Marzan AL, Nedeva C, Vennin C, Lucas MC, Cheng L, Herrmann D, Pathan M, Chisanga D, Warren SC, Zhao K, Abraham N, Anand S, Boukouris S, Adda CG, Jiang L, Shekhar TM, Baschuk N, Hawkins CJ, Johnston AJ, Orian JM, Hoogenraad NJ, Poon IK, Hill AF, Jois M, Timpson P, Parker BS, Mathivanan S. Journal name Nat Commun Publication year 2021 Sample Bovine milk Sample name Raw milk Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein mRNA miRNA tRNA Methods used in the study Western blotting Mass spectrometry Small RNA sequencing EV-TRACK -
28 Experiment ID 2816 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 34168137    Organism Bos taurus Experiment description Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Authors Samuel M, Fonseka P, Sanwlani R, Gangoda L, Chee SH, Keerthikumar S, Spurling A, Chitti SV, Zanker D, Ang CS, Atukorala I, Kang T, Shahi S, Marzan AL, Nedeva C, Vennin C, Lucas MC, Cheng L, Herrmann D, Pathan M, Chisanga D, Warren SC, Zhao K, Abraham N, Anand S, Boukouris S, Adda CG, Jiang L, Shekhar TM, Baschuk N, Hawkins CJ, Johnston AJ, Orian JM, Hoogenraad NJ, Poon IK, Hill AF, Jois M, Timpson P, Parker BS, Mathivanan S. Journal name Nat Commun Publication year 2021 Sample Bovine milk Sample name Raw milk Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
29 Experiment ID 2817 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 34168137    Organism Bos taurus Experiment description Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Authors Samuel M, Fonseka P, Sanwlani R, Gangoda L, Chee SH, Keerthikumar S, Spurling A, Chitti SV, Zanker D, Ang CS, Atukorala I, Kang T, Shahi S, Marzan AL, Nedeva C, Vennin C, Lucas MC, Cheng L, Herrmann D, Pathan M, Chisanga D, Warren SC, Zhao K, Abraham N, Anand S, Boukouris S, Adda CG, Jiang L, Shekhar TM, Baschuk N, Hawkins CJ, Johnston AJ, Orian JM, Hoogenraad NJ, Poon IK, Hill AF, Jois M, Timpson P, Parker BS, Mathivanan S. Journal name Nat Commun Publication year 2021 Sample Bovine milk Sample name Raw milk Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
30 Experiment ID 2818 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 34168137    Organism Bos taurus Experiment description Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Authors Samuel M, Fonseka P, Sanwlani R, Gangoda L, Chee SH, Keerthikumar S, Spurling A, Chitti SV, Zanker D, Ang CS, Atukorala I, Kang T, Shahi S, Marzan AL, Nedeva C, Vennin C, Lucas MC, Cheng L, Herrmann D, Pathan M, Chisanga D, Warren SC, Zhao K, Abraham N, Anand S, Boukouris S, Adda CG, Jiang L, Shekhar TM, Baschuk N, Hawkins CJ, Johnston AJ, Orian JM, Hoogenraad NJ, Poon IK, Hill AF, Jois M, Timpson P, Parker BS, Mathivanan S. Journal name Nat Commun Publication year 2021 Sample Bovine milk Sample name Raw milk Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
31 Experiment ID 2819 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 34168137    Organism Bos taurus Experiment description Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Authors Samuel M, Fonseka P, Sanwlani R, Gangoda L, Chee SH, Keerthikumar S, Spurling A, Chitti SV, Zanker D, Ang CS, Atukorala I, Kang T, Shahi S, Marzan AL, Nedeva C, Vennin C, Lucas MC, Cheng L, Herrmann D, Pathan M, Chisanga D, Warren SC, Zhao K, Abraham N, Anand S, Boukouris S, Adda CG, Jiang L, Shekhar TM, Baschuk N, Hawkins CJ, Johnston AJ, Orian JM, Hoogenraad NJ, Poon IK, Hill AF, Jois M, Timpson P, Parker BS, Mathivanan S. Journal name Nat Commun Publication year 2021 Sample Bovine milk Sample name Raw milk Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
32 Experiment ID 2823 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 34168137    Organism Bos taurus Experiment description Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Authors Samuel M, Fonseka P, Sanwlani R, Gangoda L, Chee SH, Keerthikumar S, Spurling A, Chitti SV, Zanker D, Ang CS, Atukorala I, Kang T, Shahi S, Marzan AL, Nedeva C, Vennin C, Lucas MC, Cheng L, Herrmann D, Pathan M, Chisanga D, Warren SC, Zhao K, Abraham N, Anand S, Boukouris S, Adda CG, Jiang L, Shekhar TM, Baschuk N, Hawkins CJ, Johnston AJ, Orian JM, Hoogenraad NJ, Poon IK, Hill AF, Jois M, Timpson P, Parker BS, Mathivanan S. Journal name Nat Commun Publication year 2021 Sample Bovine milk Sample name Commercial milk Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
33 Experiment ID 2824 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 34168137    Organism Bos taurus Experiment description Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Authors Samuel M, Fonseka P, Sanwlani R, Gangoda L, Chee SH, Keerthikumar S, Spurling A, Chitti SV, Zanker D, Ang CS, Atukorala I, Kang T, Shahi S, Marzan AL, Nedeva C, Vennin C, Lucas MC, Cheng L, Herrmann D, Pathan M, Chisanga D, Warren SC, Zhao K, Abraham N, Anand S, Boukouris S, Adda CG, Jiang L, Shekhar TM, Baschuk N, Hawkins CJ, Johnston AJ, Orian JM, Hoogenraad NJ, Poon IK, Hill AF, Jois M, Timpson P, Parker BS, Mathivanan S. Journal name Nat Commun Publication year 2021 Sample Bovine milk Sample name Commercial milk-derived EVs - Fraction 4 Isolation/purification methods Differential centrifugation OptiPrep density gradient centrifugation Ultracentrifugation Flotation density 1.07 g/mL Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
34 Experiment ID 2825 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 34168137    Organism Bos taurus Experiment description Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Authors Samuel M, Fonseka P, Sanwlani R, Gangoda L, Chee SH, Keerthikumar S, Spurling A, Chitti SV, Zanker D, Ang CS, Atukorala I, Kang T, Shahi S, Marzan AL, Nedeva C, Vennin C, Lucas MC, Cheng L, Herrmann D, Pathan M, Chisanga D, Warren SC, Zhao K, Abraham N, Anand S, Boukouris S, Adda CG, Jiang L, Shekhar TM, Baschuk N, Hawkins CJ, Johnston AJ, Orian JM, Hoogenraad NJ, Poon IK, Hill AF, Jois M, Timpson P, Parker BS, Mathivanan S. Journal name Nat Commun Publication year 2021 Sample Bovine milk Sample name Commercial milk-derived EVs - Fraction 5 Isolation/purification methods Differential centrifugation OptiPrep density gradient centrifugation Ultracentrifugation Flotation density 1.08 g/mL Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
35 Experiment ID 2826 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 34168137    Organism Bos taurus Experiment description Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Authors Samuel M, Fonseka P, Sanwlani R, Gangoda L, Chee SH, Keerthikumar S, Spurling A, Chitti SV, Zanker D, Ang CS, Atukorala I, Kang T, Shahi S, Marzan AL, Nedeva C, Vennin C, Lucas MC, Cheng L, Herrmann D, Pathan M, Chisanga D, Warren SC, Zhao K, Abraham N, Anand S, Boukouris S, Adda CG, Jiang L, Shekhar TM, Baschuk N, Hawkins CJ, Johnston AJ, Orian JM, Hoogenraad NJ, Poon IK, Hill AF, Jois M, Timpson P, Parker BS, Mathivanan S. Journal name Nat Commun Publication year 2021 Sample Bovine milk Sample name Commercial milk-derived EVs - Fraction 6 Isolation/purification methods Differential centrifugation OptiPrep density gradient centrifugation Ultracentrifugation Flotation density 1.10 g/mL Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
36 Experiment ID 2827 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 34168137    Organism Bos taurus Experiment description Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Authors Samuel M, Fonseka P, Sanwlani R, Gangoda L, Chee SH, Keerthikumar S, Spurling A, Chitti SV, Zanker D, Ang CS, Atukorala I, Kang T, Shahi S, Marzan AL, Nedeva C, Vennin C, Lucas MC, Cheng L, Herrmann D, Pathan M, Chisanga D, Warren SC, Zhao K, Abraham N, Anand S, Boukouris S, Adda CG, Jiang L, Shekhar TM, Baschuk N, Hawkins CJ, Johnston AJ, Orian JM, Hoogenraad NJ, Poon IK, Hill AF, Jois M, Timpson P, Parker BS, Mathivanan S. Journal name Nat Commun Publication year 2021 Sample Bovine milk Sample name Commercial milk-derived EVs - Fraction 7 Isolation/purification methods Differential centrifugation OptiPrep density gradient centrifugation Ultracentrifugation Flotation density 1.12 g/mL Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
37 Experiment ID 2828 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Western blotting PubMed ID 34168137    Organism Bos taurus Experiment description Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Authors Samuel M, Fonseka P, Sanwlani R, Gangoda L, Chee SH, Keerthikumar S, Spurling A, Chitti SV, Zanker D, Ang CS, Atukorala I, Kang T, Shahi S, Marzan AL, Nedeva C, Vennin C, Lucas MC, Cheng L, Herrmann D, Pathan M, Chisanga D, Warren SC, Zhao K, Abraham N, Anand S, Boukouris S, Adda CG, Jiang L, Shekhar TM, Baschuk N, Hawkins CJ, Johnston AJ, Orian JM, Hoogenraad NJ, Poon IK, Hill AF, Jois M, Timpson P, Parker BS, Mathivanan S. Journal name Nat Commun Publication year 2021 Sample Bovine milk Sample name Commercial milk-derived EVs - Fraction 8 Isolation/purification methods Differential centrifugation OptiPrep density gradient centrifugation Ultracentrifugation Flotation density 1.16 g/mL Molecules identified in the study Protein Methods used in the study Western blotting EV-TRACK -
38 Experiment ID 2815 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 34168137    Organism Bos taurus Experiment description Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Authors Samuel M, Fonseka P, Sanwlani R, Gangoda L, Chee SH, Keerthikumar S, Spurling A, Chitti SV, Zanker D, Ang CS, Atukorala I, Kang T, Shahi S, Marzan AL, Nedeva C, Vennin C, Lucas MC, Cheng L, Herrmann D, Pathan M, Chisanga D, Warren SC, Zhao K, Abraham N, Anand S, Boukouris S, Adda CG, Jiang L, Shekhar TM, Baschuk N, Hawkins CJ, Johnston AJ, Orian JM, Hoogenraad NJ, Poon IK, Hill AF, Jois M, Timpson P, Parker BS, Mathivanan S. Journal name Nat Commun Publication year 2021 Sample Bovine milk Sample name Raw milk Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein mRNA miRNA tRNA Methods used in the study Western blotting Mass spectrometry Small RNA sequencing EV-TRACK -
39 Experiment ID 2822 Identified molecule protein Extracellular vesicle type Extracellular vesicles MISEV Small EVs Identification method Mass spectrometry PubMed ID 34168137    Organism Bos taurus Experiment description Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis Authors Samuel M, Fonseka P, Sanwlani R, Gangoda L, Chee SH, Keerthikumar S, Spurling A, Chitti SV, Zanker D, Ang CS, Atukorala I, Kang T, Shahi S, Marzan AL, Nedeva C, Vennin C, Lucas MC, Cheng L, Herrmann D, Pathan M, Chisanga D, Warren SC, Zhao K, Abraham N, Anand S, Boukouris S, Adda CG, Jiang L, Shekhar TM, Baschuk N, Hawkins CJ, Johnston AJ, Orian JM, Hoogenraad NJ, Poon IK, Hill AF, Jois M, Timpson P, Parker BS, Mathivanan S. Journal name Nat Commun Publication year 2021 Sample Bovine milk Sample name Commercial milk Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein mRNA miRNA tRNA Methods used in the study Mass spectrometry Small RNA sequencing EV-TRACK -